Clinical Pathology and Treatment of Renin-Angiotensin System 4. Renin-Angiotensin System and Insulin Resistance

Renin-angiotensin system and unilateral ureteral obstruction

Unilateral ureteral obstruction (UUO) is a clinical scenario that leads to obstructive nephropathy. UUO alters the expression of many mediators in the ipsilateral kidney. Renin-angiotensin system (RAS) is involved in UUO. Angiotensin II (Ang II) and angiotensin 1-7 (Ang 1-7) as the main arms of RAS influence kidney function which may alter by UUO. Ang II via Ang II receptor subtypes I (AT1R) ...

Clinical pathology and treatment of renin-angiotensin system 3. Atherosclerosis and the renin-angiotensin system.

Atherosclerosis is an inflammatory disease characterized by endothelial dysfunction, thereby leading to the accumulation of macrophage-derived foam cells in the vessel wall. Endothelial cells, intimal smooth muscle cells, and leukocytes produce a wide range of inflammatory cytokines, chemokines, and growth factors in the multifactorial process of atherosclerosis. Angiotensin II (Ang II) has bee...

Renin - Angiotensin - Aldosterone System

Chronic heart failure (CHF) is associated with endothelial dysfunction. Activation of the renin-angiotensin-aldosterone system (RAAS) is believed to be important in the deterioration of endothelial dysfunction in CHF through stimulation of oxidative stress. Whereas angiotensin-converting enzyme inhibitors (ACE-I) improve endothelial function in CHF, the effects of angiotensin II AT 1-receptor b...

Renin - Angiotensin - Aldosterone System

http://jra.sagepub.com/content/10/1/24 The online version of this article can be found at: DOI: 10.1177/1470320309104067 2009 10: 24 Journal of Renin-Angiotensin-Aldosterone System Manuel Labiós, Marcial Martínez, Francisco Gabriel, Victoria Guiral, Francisco Dasi, Belén Beltrán and Anna Muñoz patients: effects of eprosartan treatment Superoxide dismutase and catalase anti-oxidant activity in l...

Brain Renin–Angiotensin System